An asymmetric total synthesis of Prostaglandin E 1 (5) has with the Corey CBS catalyst gave the Ο-side chain 7 with ΟΎ96% ee. Conjugate addition using the reaction with been achieved in a two-component coupling process. The chiral hydroxycyclopentenone 6 was readily available from dilithiocyanocuprat
β¦ LIBER β¦
ChemInform Abstract: An Efficient Asymmetric Synthesis of Prostaglandin E1.
β Scribed by Ana Rodriguez; Miguel Nomen; Bernd Werner Spur; Jean-Jacques Godfroid
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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