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ChemInform Abstract: An Asymmetric Synthesis of (+)-Apogossypol Hexamethyl Ether.

โœ Scribed by A. I. MEYERS; J. J. WILLEMSEN


Book ID
112032454
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: An Asymmetric Synth
โœ B. M. TROST; G. R. COOK ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 2 views

An Asymmetric Synthesis (-)-Epibatidine. -The title compound (X) is synthesized with a view to its biological activity and its low natural abundance. Key steps in this synthesis are the Pd-catalyzed desymmetrization of the dibenzoate (I) and the Pd-catalyzed cross coupling of the vinyl bromide (V)