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ChemInform Abstract: An Approach to Epothilones Based on Olefin Metathesis.

โœ Scribed by K. C. NICOLAOU; Y. HE; D. VOURLOUMIS; H. VALLBERG; Z. YANG


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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An Approach to Epothilones Based on Olef
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ChemInform Abstract: Total Synthesis of
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Total Synthesis of Epothilone A: The Olefin Metathesis Approach. -Starting with the three building blocks (I)-(III) the coupling product (IV) is obtained. It is used for olefin metathesis as the key step in the synthesis of the title compound (VI). -(YANG, Z.;