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ChemInform Abstract: Amination of α,β-Unsaturated (2-Trimethylsilanylmethyl) Carboxylic Esters.

✍ Scribed by Tecla Gasperi; M. Antonietta Loreto; Paolo A. Tardella; Augusto Gambacorta

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Dihydrox
ChemInform Abstract: Asymmetric Dihydroxylation onto the α,β-Unsaturated Carboxylic Ester Derivatives of Camptothecin.
✍ K. TAGAMI; S. TAKAGI; S. SANO; M. SHIRO; Y. NAGAO 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 37 KB

Asymmetric Dihydroxylation onto the α,β-Unsaturated Carboxylic Ester Derivatives of Camptothecin. -The title investigation is presented in context with studies on the preparation of camptothecin derivatives applicable as clinical antitumor agents. Compounds (IIa) and (IIIa) exhibit strong antitumor