Selective borohydride reduction of adenosine dialdehyde (1) gave the known adenosine 2'monoaldehyde (2). Reaction of I with N,N'-diphenylethylenediamine, followed by reduction and deblocking gave adenosine 3'-monoaldehyde ($), a new compound. Unlike 2, compound $ inhibited S-AdoHcy hydrolase and sho
β¦ LIBER β¦
ChemInform Abstract: Adenosine Dialdehyde Analogues. Part 1. Regioselective Synthesis of Adenosine Monoaldehydes.
β Scribed by J. P. NEENAN; S. M. OPITZ; C. L. COOKE; M. A. USSERY; T. C. MORRILL; L. M. ECKEL
- Book ID
- 112039014
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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