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ChemInform Abstract: Adenosine Dialdehyde Analogues. Part 1. Regioselective Synthesis of Adenosine Monoaldehydes.

✍ Scribed by J. P. NEENAN; S. M. OPITZ; C. L. COOKE; M. A. USSERY; T. C. MORRILL; L. M. ECKEL


Book ID
112039014
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
27
Category
Article
ISSN
0931-7597

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Selective borohydride reduction of adenosine dialdehyde (1) gave the known adenosine 2'monoaldehyde (2). Reaction of I with N,N'-diphenylethylenediamine, followed by reduction and deblocking gave adenosine 3'-monoaldehyde ($), a new compound. Unlike 2, compound $ inhibited S-AdoHcy hydrolase and sho

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v