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ChemInform Abstract: A Three-Step Synthesis of Cerpegin (VII).

โœ Scribed by H. HONG; D. L. COMINS


Book ID
112031896
Publisher
John Wiley and Sons
Year
2010
Weight
26 KB
Volume
27
Category
Article
ISSN
0931-7597

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One-pot three steps synthesis of cerpegi
โœ Didier Villemin; Liang Liao ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 113 KB

Cerpegin 1 was synthesized in a one-pot reaction at room temperature catalysed by cesium carbonate with an overall of 75% yield. 3-Hydroxy-3-methyl-2-butanone 2 reacted with diethyl malonate 3 to give 2-ethoxycarbonyl-3,4,4-trimethyl-2-buten-4-olide 4. Then 4 with s-triazine gave to I,l-dimethylfuro