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ChemInform Abstract: A Synthetic Strategy for the Cyclodepsipeptide Core of the Antitumor Antibiotic Verucopeptin.

โœ Scribed by Karl J. Hale; Linos Lazarides; Jiaqiang Cai

Publisher
John Wiley and Sons
Year
2010
Weight
23 KB
Volume
33
Category
Article
ISSN
0931-7597

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โœ R. S. COLEMAN; A. J. CARPENTER ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 1 views

The Development of Strategies for Construction of the Aziridine Core of the Antitumor Agents Azinomycins A and B. -The key steps in the synthesis of the aziridine (VII) are Wadsworth-Horner-Emmons olefination to form the derivative (III), its bromination to the (E)-isomer (IV), and cyclization of th