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ChemInform Abstract: A Soft Spot for Alkynes

✍ Scribed by U. H. F. BUNZ


Book ID
101860601
Publisher
John Wiley and Sons
Year
2010
Weight
22 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Convergent Approa
✍ J. BOIVIN; S. HUPPE; S. Z. ZARD πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 34 KB πŸ‘ 1 views

The convergent approach to a broad variety of functionalized alkynes starts with a Knoevenagel-type condensation of 4-unsubstituted isoxazolines with ketones or aldehydes. The resulting adducts are subjected to Michael addition with various nucleophiles such as hydride, cyanide or phosphite. Exposur