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ChemInform Abstract: A Short Synthesis of (S)-2-(Diphenylmethyl)pyrrolidine, a Chiral Solvating Agent for NMR Analysis.

✍ Scribed by D. J. BAILEY; D. O'HAGAN; M. TAVASLI


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Reductive Cyanation
✍ J.-O. DURAND; M. LARCHEVEQUE; Y. PETIT πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB

Reductive Cyanation: A Key Step for a Short Synthesis of (-)-(2S,3S)-3-Hydroxyproline. -A short, stereoselective synthesis of a 3-hydroxyproline (VII) starting from L-malic acid is described. Key step is a stereospecific reductive cyanation of compound (IV), which leads in contrast to former studie