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ChemInform Abstract: A Short Formal Synthesis of Squalamine from a Microbial Metabolite.

โœ Scribed by William A. Kinney; Xuehai Zhang; Jon I. Williams; Sean Johnston; Ronald S. Michalak; Milind Deshpande; Larry Dostal; John P. N. Rosazza


Publisher
John Wiley and Sons
Year
2001
Weight
31 KB
Volume
32
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Formal Synthesis
โœ Y.-G. SUH; J.-K. JUNG; B.-C. SUH; Y.-C. LEE; S.-A. KIM ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 35 KB ๐Ÿ‘ 2 views

A Formal Synthesis of (+)-Brefeldin A. -An advanced synthetic intermediate for (+)-brefeldin A (IX) is efficiently synthesized from Weinreb amide (I). The procedure involves the highly stereoselective construction of the hydroxycyclopentane moiety via an oxabicycloheptanone unit. -(SUH,