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ChemInform Abstract: A Short, Efficient Synthesis of Monofluoro Ketomethylene Peptide Isostere Core Units.

โœ Scribed by R. V. HOFFMAN; J. E. SAENZ

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
29
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Title compounds of type (VII) (6 examples) are readily prepared following the 4-step sequence presented. The introduction of the fluorine substituent is best achieved using selectfluor under the optimized conditions shown.

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