ChemInform Abstract: A Practical Synthesis of (R)-(-)-Phenylephrine Hydrochloride.

✍ Scribed by Mukund K. Gurjar; L. Murali Krishna; Bugga V. N. B. S. Sarma; Mukund S. Chorghade

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 28 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199913285

✦ Synopsis

A Practical Synthesis of (R)-(-)-Phenylephrine Hydrochloride.

-An asymmetric synthesis of title compound (IV) is developed based on hydrolytic kinetic resolution of the styrene oxide (I) using a (R,R)-Salen-Co-OAc complex. -(GURJAR, MUKUND K.;