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ChemInform Abstract: A Practical Route to Enantiopure, Highly Functionalized Seven-Membered Carbocycles and Tetrahydrofurans: Concise Synthesis of (+)-Nemorensic Acid.

✍ Scribed by Fernando Lopez; Luis Castedo; Jose L. Mascarenas


Publisher
John Wiley and Sons
Year
2010
Weight
42 KB
Volume
33
Category
Article
ISSN
0931-7597

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A Practical Route to Enantiopure, Highly
✍ Fernando LΓ³pez; Luis Castedo; JosΓ© L. MascareΓ±as πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 340 KB πŸ‘ 1 views

Highly diastereoselective thermal [5C2C] intramolecular pyrone Β± alkene cycloadditions can be achieved by introducing a homochiral ptolylsulfinyl group at a suitable position of the alkene. The resulting adducts can be readily desulfinylated to give optically active 8-oxabicyclo[3.2.1]octane derivat