A Practical Route to Enantiopure, Highly
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Fernando LΓ³pez; Luis Castedo; JosΓ© L. MascareΓ±as
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Article
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2002
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John Wiley and Sons
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English
β 340 KB
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Highly diastereoselective thermal [5C2C] intramolecular pyrone Β± alkene cycloadditions can be achieved by introducing a homochiral ptolylsulfinyl group at a suitable position of the alkene. The resulting adducts can be readily desulfinylated to give optically active 8-oxabicyclo[3.2.1]octane derivat