Palladium-catalyzed crosscoupling reactions of 2-bromocyclohex-1-enyl triflates 7 and 11 with a variety of alkenylstannanes occurred chemoselectively at the site of the triflate leaving group to give bromobutadienes which readily underwent Heck reactions with acrylates and styrene. Both steps could
ChemInform Abstract: A One-Pot Sequence of Stille and Heck Couplings: Synthesis of Various 1,3,5-Hexatrienes and Their Subsequent 6π-Electrocyclizations.
✍ Scribed by Paultheo von Zezschwitz; Frauke Petry; Armin de Meijere
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 45 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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📜 SIMILAR VOLUMES
1,6-Disubstituted (E,Z,E)-1,3,5-hexatrienes (4 and 5) were hex-1-ene (19) or by Wittig-Horner-Emmons olefination of 2bromocyclohexene-1-carbaldehyde ( 24) and subsequent prepared by vicinal twofold Heck coupling reactions from 1,2-dibromocyclopentene (1), 1,2-dibromocyclohexene (2), Heck reaction of