ChemInform Abstract: The Twofold Heck Reaction on 1,2-Dihalocycloalkenes and Subsequent 6π-Electrocyclization of the Resulting (E,Z,E)-1,3,5-Hexatrienes: A New Formal {2 + 2 + 2}-Assembly of Six-Membered Rings.

The Twofold Heck Reaction on 1,2-Dihaloc

The Twofold Heck Reaction on 1,2-Dihalocycloalkenes and Subsequent 6π-Electrocyclization of the Resulting (E, Z, E)-1,3,5-Hexatrienes: A New Formal {2+2+2}-Assembly of Six-Membered Rings

✍ Katharina Voigt; Paultheo von Zezschwitz; Keith Rosauer; Annegret Lansky; Amy Ad 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 490 KB 👁 1 views

1,6-Disubstituted (E,Z,E)-1,3,5-hexatrienes (4 and 5) were hex-1-ene (19) or by Wittig-Horner-Emmons olefination of 2bromocyclohexene-1-carbaldehyde ( 24) and subsequent prepared by vicinal twofold Heck coupling reactions from 1,2-dibromocyclopentene (1), 1,2-dibromocyclohexene (2), Heck reaction of