ChemInform Abstract: A Novel Super-Potent Neurokinin A Receptor Antagonist Containing Dehydroalanine
β Scribed by A. LOMBARDI; B. D'AGOSTINO; F. NASTRI; L. D. D'ANDREA; A. FILIPPELLI; M. FALCIANI; F. ROSSI; V. PAVONE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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High Affinity, Selective Neurokinin 2 and Neurokinin 3 Receptor Antagonists from a Common Structural Template. -Starting from a common lactam (I) two types of neurokinin receptor antagonists (IV) and (V) can be prepared by simple reaction sequences. Derivatives (V) are found to be selective potent
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