ChemInform Abstract: A Novel Reductive Ring-Opening Reaction of Isoxazolidine to Form Functionalized 1,3-Amino-alcohol.
β Scribed by Hong Kui Zhang; Wing Hong Chan; Albert W. M. Lee; Ping Fang Xia; Wai Yeung Wong
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 41 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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π SIMILAR VOLUMES
Substituted isoxazolidinium salts 6-14 undergo ring-opening reaction when treated with lithium iodide to yield 13-amino alcohols 15-23 having multiple c h i d centres. The overall process proceeds through a probable single-electron-transfer mechanism with the redox system being the N,O-heterocyclic