ChemInform Abstract: A Diastereoselectiv
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K. GOODALL; A. F. PARSONS
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Article
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2010
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John Wiley and Sons
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A Diastereoselective Radical Cyclization Approach to Pyroglutamates. -The 5-endo radical cyclization of pyruvic acid derived dehydroalanines (VI) possessing chiral ester auxiliaries is reported. The diastereoselectivity can be increased up to 6:1 by cyclization of the corresponding 8-phenylmenthyl