ChemInform Abstract: A Novel, Facile and Diastereoselective Synthesis of (3S, 4S) and (3R,4S)-N-Me-AHPPA.
β Scribed by G. Vidyasagar Reddy; G. Venkat Rao; D. S. Iyengar
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Synthesis of (2S,3R,4S)-3,4-Methanoproline and Analogues by Cyclopropylidene Insertion. -The key steps in the synthesis of the title compounds (IX), (XIII), and (XVI) are stereoselective cyclization of the bromides (V), (X), and (XIV) and oxidation of the bicyclic derivatives (VIII), (XII), and (XV