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ChemInform Abstract: A Novel Arylethynyltriazole Acyclonucleoside Inhibits Proliferation of Drug-Resistant Pancreatic Cancer Cells.

✍ Scribed by Menghua Wang; Yi Xia; Yuting Fan; Palma Rocci; Fangi Qu; Juan L. Iovanna; Ling Peng


Publisher
John Wiley and Sons
Year
2011
Weight
31 KB
Volume
42
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES


A novel arylethynyltriazole acyclonucleo
✍ Menghua Wang; Yi Xia; Yuting Fan; Palma Rocchi; Fanqi Qu; Juan L. Iovanna; Ling πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 767 KB

Novel arylethynyltriazole acyclonucleosides were synthesized and assessed for their anticancer activity on drug-resistant pancreatic cancer MiaPaCa-2 cells. One lead compound was found to have much more potent apoptosis-related antiproliferative effects than gemcitabine, the current first-line treat