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ChemInform Abstract: A Novel and Facile Reaction to N6-Alkylated Adenosine via Benzotriazole as a Synthetic Auxiliary.

✍ Scribed by Hanan M. N. M. Afify; Erik B. Pedersen; Magdy A. Zahran

Publisher: John Wiley and Sons
Year: 2010
Weight: 33 KB
Volume: 31
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200035205

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## Abstract The reaction of benzotriazole with aliphatic, aromatic or heteroaromatic aldehyde and adenosine leads to a benzotriazole adduct which is reduced with sodium borohydride to the corresponding __N__^6^‐alkylated adenosine derivatives. This procedure is also utilized in a new route to __N__

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