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ChemInform Abstract: A New Strategy for the Elaboration of Pyrrolidine N-Oxides Using the Reverse-Cope Elimination.

โœ Scribed by J. R. HANRAHAN; D. W. KNIGHT


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A New, Stereoselect
โœ A. R. WHEILDON; D. W. KNIGHT; M. P. LEESE ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 1 views

I) and addition of nitrones (II) results in a smooth condensation to give the unsaturated hydroxylamines (III) stereoselectively. These undergo reverse-Cope cyclizations at room temperature leading to the diastereomeric mixture of pyrrolidine-N-oxides (IV) and (V). -