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ChemInform Abstract: A New Route to Substituted Pyrimido[5,4-e]-1,2,4-triazine-5,7(1H,6H)-diones and Facile Extension to 5,7(6H,8H) Isomers.

✍ Scribed by Anjanette J. Turbiak; H. D. Hollis Showalter

Publisher: John Wiley and Sons
Year: 2010
Weight: 59 KB
Volume: 41
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201016160

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## Facile Synthesis of 6-Aryl-1,3-dimethyl-5H-pyrimido[4,5b][1,4]diazepine-2,4(1H,3H)-diones. -A new approach to the regioselective synthesis of the title compounds (IV) starting from readily accessible 6-amino-5-benzylideneaminopyrimidines (I) is described. Condensation of compound (I) with diet