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ChemInform Abstract: A New Entry to Hydroxylated Pyrrolizidines.

โœ Scribed by John K. Gallos; Vassiliki C. Sarli; Theocharis V. Koftis; Evdoxia Coutouli-Argyropoulou


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Cyclopropenone Ro
โœ A. KASCHERES; H. C. SCHUMACHER; R. A. F. RODRIGUES ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 28 KB

A Cyclopropenone Route to New Pyrrolizidine Derivatives. -Enaminone (I) is converted to pyrrol-2-one (III) with the substituted cyclopropenone (II). Via a subsequent acidic intramolecular aldol reaction bicyclic dihydropyrrolones (IV) and (V) are easily obtained when HCl is employed. With TFA selec