ChemInform Abstract: A New, Efficient Exocyclic Amine Protection Scheme for 2-Aminoadenosine and Derivatives for Incorporation into Oligonucleotides
β Scribed by Bruce S. Ross; Robert H. Springer; Ramesh Bharadwaj; Alice M. Symons; Muthiah Manoharan
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
The readily installed, fluoride labile protecting group Tsoc (-CO-O-Si(iPr) 3 ) for basic nitrogen is presented. Deprotection of Tsoc carbamates is orthogonal to the conditions used for deprotection of Boc,
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Butane Diacetal Protected Butane Tetrol Derivatives. -Novel 2,3-butane diacetal-protected trihydroxybutanal (V) [and ent-(V) on analogous ways] is prepared in multigram scale starting from the corresponding protected dimethyl tartrate (I). The approach involves reduction of the diester to the corre