ChemInform Abstract: A New Class of Anti-HIV Agents: Synthesis and Activity of Conjugates of HIV Protease Inhibitors with a Reverse Transcriptase Inhibitor.
β Scribed by Tooru Kimura; Hikaru Matsumoto; Takashi Matsuda; Tomonori Hamawaki; Kenichi Akaji; Yoshiaki Kiso
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
The effects of substituent modification on HIV-1 reverse transcriptase (RT) inhibitory activities of a series of pyrimidine derivatives, e.g. (I)-(IV), are studied. In comparison with reference compound delavirdine (DLV), compounds (Ia), (II), and (IIIa)-(IIIc) show the most potent in vitro inhibito
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