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ChemInform Abstract: A New Bromo Trienyne: Synthesis of all-E, Conjugated Tetra-, Penta-, and Hexaenes Common to Oxo Polyene Macrolide Antibiotics.

โœ Scribed by B. H. LIPSHUTZ; B. ULLMAN; C. LINDSLEY; S. PECCHI; D. J. BUZARD; D. DICKSON


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Streamlined Route
โœ B. H. LIPSHUTZ; C. LINDSLEY ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB ๐Ÿ‘ 2 views

A Streamlined Route to Highly Conjugated, all-(E) Polyenes Characteristic of Oxo Polyene Macrolide Antibiotics. -Couplings at the vinyl stannane end in the readily available organometallic linchpin (I) can be carried out with vinyl halides following two basic methods. The terminal acetylene in thes