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ChemInform Abstract: A Highly Stereoselective Construction of β-Glycosyl Linkages by Reductive Cleavage of Cyclic Sugar Orthoesters.

✍ Scribed by Hiro Ohtake; Naoto Ichiba; Shiro Ikegami


Publisher
John Wiley and Sons
Year
2001
Weight
43 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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ChemInform Abstract: A Highly Stereosele
✍ T. IIMORI; H. OHTAKE; S. IKEGAMI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB

A Highly Stereoselective β-(1→4)-Glycosidic Bond Formation by Reductive Cleavage of Cyclic Orthoesters. -Reduction of the orthoester (I) under the conditions shown provides the desired glycoside (II) with high β-selectivity. Application of a LiAlH4/AlCl3 reagent to the glycosidic spiro-orthoesters