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ChemInform Abstract: A Highly Efficient Synthesis of L-β-2′-Deoxy-4′-thio-1′-purine Nucleosides as Potential Antiviral Agents.

✍ Scribed by Hea Ok Kim; Lak Shin Jeong; Sun Nan Lee; Soo Jeong Yoo; Hyung Ryong Moon; Kil Soo Kim; Moon Woo Chun


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Antiv
✍ H. SATOH; Y. YOSHIMURA; M. WATANABE; N. ASHIDA; K. IJICHI; S. SAKATA; H. MACHIDA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 40 KB 👁 2 views

Synthesis and Antiviral Activities of 5-Substituted 1-(2-Deoxy-2-C-methylene-4-thio-β-D-erythro-pentofuranosyl) uracils. -A variety of the title nucleosides [cf. (VII)/(VIII), (X)] are prepared using sila-Pummerer-type glycosylation as key step. The majority of the β-anomers of these nucleosides po