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ChemInform Abstract: A Highly Efficient Methodology for 5-Methyl-3-aryl-2-thiooxazolidin-4-ones Using Lithium Perchlorate in DIPEA Mediated Synthesis.

✍ Scribed by Gopal L. Khatik; Anang Pal; Tushar D. Apsunde; Vipin A. Nair

Book ID
102058372
Publisher
John Wiley and Sons
Year
2010
Weight
21 KB
Volume
41
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

Aryl isothiocyanates (III) are converted to the title compounds (V) by treating with ethyl lactate (IV) in the presence of a base and a catalytic amount of lithium perchlorate.

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A highly efficient methodology for 5-met
A highly efficient methodology for 5-methyl-3-aryl-2-thiooxazolidin-4-ones using lithium perchlorate in DIPEA mediated synthesis
✍ Gopal L. Khatik; Anang Pal; Tushar D. Apsunde; Vipin A. Nair 📂 Article 📅 2010 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 139 KB

## Abstract magnified image An efficient methodology for the synthesis of 5‐methyl‐3‐aryl‐2‐thiooxazolidin‐4‐ones from aryl isothiocyanates has been developed. Aryl isothiocyanates, synthesized from various anilines, were converted to the desired compounds by treating with ethyl lactate in presence