5-Thio-L-fucopyranose tetraacetate was synthesized in 11 steps from 5-O-trityl-D-arabinofuranose or D-arabinose diethyl dithioacetal by one-carbon elongation at C-5. Highly diastereoselective addition of MeLi in ether to a 1,2-O-isopropylidene-[J-D-arabino-pentodialdo-l,4-furanose derivative was ach
ChemInform Abstract: A Facile Synthesis of 5-Thio-L-fucose and 5-Thio-D-arabinose from D- Arabinose.
β Scribed by M. IZUMI; O. TSURUTA; H. HASHIMOTO
- Book ID
- 112030656
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
The efficient synthesis of sugar-derived triazoles via a one-pot substitution-cyclization-oxidation procedure is presented. Starting from D-arabinose and L-fucose, triazole structures as potential enzyme inhibitors were obtained in six to eight steps.
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