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ChemInform Abstract: A Facile Synthesis of [1,2,4]Triazino[4,5-a]benzimidazoles, Pyrazolo[5,1-c]triazines, Triazolo[5,1-c]triazines and Pyrido[1,2-a]benzimidazoles.

✍ Scribed by Abdou O. Abdelhamid; Hussein F. Zohdi; Mahmoud M. Ziada

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
31
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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Synthesis and reactivity of cyanomethyl
Synthesis and reactivity of cyanomethyl 2-amino-4-methylthiazolyl ketone. A facile synthesis of novel pyrazolo[5,1-c]1,2,4-triazine, 1,2,4-triazolo[5,1-c]1,2,4-triazine, 1,2,4-triazino[4,3-a]benzimidazole, pyridazine-6-imine and 6-oxopyridazinone derivatives
✍ Samia M. Sayed; Mohamed A. Raslan; Mohamed A. Khalil; Kamal M. Dawood πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 168 KB πŸ‘ 2 views

The novel and versatile cyanomethyl 2amino-4-methylthiazolyl ketone (5) was prepared by treatment of bromomethyl 2-amino-4-methyl thiazolyl ketone (4) with potassium cyanide. Reaction of 5 with heterocyclic diazonium salts 6a,b and 10 afforded the corresponding hydrazones 7a,b and 11, respectively.