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ChemInform Abstract: A Facile Preparation of a Combinatorial Library of 2,6-Disubstituted Triazines.

✍ Scribed by T. MASQUELIN; Y. DELGADO; V. BAUMLE

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

A Facile Preparation of a Combinatorial Library of 2,6-Disubstituted Triazines. -Base-catalyzed cyclization of the bis-nucleophilic thiouronium salts (I) and following amination of the resulting triazines (II) via intermediate oxidation to 2-(alkylsulfinyl) triazines provides an efficient preparation of unsymmetrically substituted 2,6-diamino-1,3,5-triazines (IV). -(MASQUELIN,

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