ChemInform Abstract: A Facile Pathway to Enantiomerically Enriched 3-Hydroxy-2-oxindoles: Asymmetric Intramolecular Arylation of α-Keto Amides Catalyzed by a Palladium—DifluorPhos Complex.

✍ Scribed by Liang Yin; Motomu Kanai; Masakatsu Shibasaki

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 61 KB
• Volume: 43
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201201091

✦ Synopsis

Abstract

The method is applicable to aryl triflates bearing different aromatic and aliphatic substituents, as well as sterically hindered β‐keto amide (XII).