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ChemInform Abstract: A Facile Construction of 4-Hydroxymethylbenzisothiazolone-1,1-dioxide.

โœ Scribed by K.-S. YEUNG; N. A. MEANWELL; Y. LI; Q. GAO

Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Synthesis of 4-Th
ChemInform Abstract: A Synthesis of 4-Thiomethylbenzisothiazolone-1,1-dioxide Using HDPT.
โœ K.-S. YEUNG; N. A. MEANWELL ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 1 views

A Synthesis of 4-Thiomethylbenzisothiazolone-1,1-dioxide Using HDPT. -The title compounds (V), required for pharmaceutical studies, are efficiently prepared starting with regioselective benzylic bromination of the corresponding dioxides (I). Coupling of the resulting benzyl bromides with HDPT (III)