ChemInform Abstract: A Facile and Efficient Oxalyldihydrazide/Ketone-Promoted Copper-Catalyzed Amination of Aryl Halides in Water.
β Scribed by Xinhai Zhu; Li Su; Liye Huang; Gong Chen; Jinlong Wang; Huacan Song; Yiqian Wan
- Publisher
- John Wiley and Sons
- Year
- 2009
- Weight
- 48 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The easy availability of the ligand, the commercially available cheap copper source, the use of a green solvent and aqueous ammonia as the readily available nitrogen source are features of this protocol.
## Abstract The __N^2^,N^2^β²__βdiisopropyloxalohydrazide/CuO system efficiently catalyzed the direct amination of aryl bromides andiodides with aqueous ammonia in water at 60 Β°C in 24 h or at 120 Β°C in only 20β30 min. Both activated and unactivated aryl and heteroaryl bromides and iodides were read