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ChemInform Abstract: A Corticoid Synthesis from 9α-Hydroxyandrost-4-ene-3,17-dione via a Steroidal Allene.

✍ Scribed by D. R. ANDREWS; R. A. GIUSTO; A. R. SUDHAKAR


Book ID
112036379
Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
27
Category
Article
ISSN
0931-7597

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Synthesis of 6α-Methyl-16α,17α-cyclohexanoprogesterone via γ-Methylenation of 16α,17. alpha.-Cyclohexanopregn-4-ene-3,20-dione. -An improved synthetic way to the title cyclohexanoprogesterone (IV) is presented. The introduction of the 6α-methyl group is achieved by regioselective γ-methylenation of