ChemInform Abstract: A Copper-Mediated Cyclization Reaction of Hydrazine with Enediynones Providing Pyrazolo[1,5-a]pyridines.
β Scribed by Hung-Chou Wu; Long-Chih Hwang; Ming-Jung Wu
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 29 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
2,7βDisubstituted pyrazolopyridines (II) and (IV) are synthesized in moderate to good yields by a cascade cyclization reaction of enediynones (I) and (III) with hydrazine, promoted by copper chloride.
π SIMILAR VOLUMES
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Reaction of 5-Aminopyrazoles with Ξ²-Dimethylaminopropiophenones. Synthesis of New Pyrazolo [3,4-b]pyridines. -Reaction of 5aminopyrazoles (I) with Ξ²-aminopropiophenones (II) provides a new and simple synthetic entry into the pyrazolo[3,4-b]pyridine ring system. Oxidation of the dihydro-products (II