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ChemInform Abstract: A Convenient Synthesis of Racemic 2′-Deoxy Carbocyclic Thymidines Lacking the 5′-Methylene Group.

✍ Scribed by J. ZHOU; P. B. SHEVLIN


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis and Antiv
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Synthesis and Antiviral Activities of 5-Substituted 1-(2-Deoxy-2-C-methylene-4-thio-β-D-erythro-pentofuranosyl) uracils. -A variety of the title nucleosides [cf. (VII)/(VIII), (X)] are prepared using sila-Pummerer-type glycosylation as key step. The majority of the β-anomers of these nucleosides po