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ChemInform Abstract: A Convenient Synthesis of Oxazolidinone Derivatives Linezolid and Eperezolid from (S)-Glyceraldehyde Acetonide.

✍ Scribed by Guangyu Xu; Yi Zhou; Chunhao Yang; Yuyuan Xie

Book ID
102020437
Publisher
John Wiley and Sons
Year
2008
Weight
31 KB
Volume
39
Category
Article
ISSN
0931-7597

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πŸ“œ SIMILAR VOLUMES

A convenient synthesis of oxazolidinone
A convenient synthesis of oxazolidinone derivatives linezolid and eperezolid from (S)-glyceraldehyde acetonide
✍ Guangyu Xu; Yi Zhou; Chunhao Yang; Yuyuan Xie πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 146 KB

## Abstract A new convenient method for the synthesis of oxazolidinone antibacterials Linezolid and Eperezolid from readily available (S)‐glyceraldehyde acetonide was developed. The key steps include reductive amination of arylamine and (__S__)‐glyceraldehyde acetonide in the presence of NaBH~4~ an

ChemInform Abstract: A Short Synthesis o
ChemInform Abstract: A Short Synthesis of Oxazolidinone Derivatives Linezolid and Eperezolid: A New Class of Antibacterials.
✍ Braj B. Lohray; Sundarababu Baskaran; B. Srinivasa Rao; B. Yadi Reddy; I. Negesw πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 2 views

Starting from the D-mannitol derivative (I), a straightforward synthesis of the chiral oxazolidines (VII) including precursors (VIIb) and (VIIc) of linezolid and eperezolid is detailed. Furthermore, the azide (VIIb) is converted to linezolid (IX) with thioacetic acid.

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ChemInform Abstract: A Convenient Synthesis of Selenocarboxamides from Nitriles.
✍ Rafal Kaminski; Richard S. Glass; Aleksandra Skowronska πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v