ChemInform Abstract: A Convenient Synthesis of (-)-Methyl Epijasmonate.

✍ Scribed by J. S. U; H. S. PARK; S. GUPTA; J. K. CHA

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 34 KB
• Volume: 28
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199747264

✦ Synopsis

A Convenient Synthesis of (-)-Methyl Epijasmonate.

-A short, enantioselective synthesis of the title "isoprostane" (XII) starting from commercially available Corey lactone aldehyde (I) is given. The key features of the sequence are the stereoselective construction of the 2,3-cis-disubstituted cyclopentanone system by hydrogenation of dienoate (IV) and the subsequent one-carbon degradation (V)→(VIII). -(U,