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ChemInform Abstract: A Convenient Procedure for the Synthesis of N-Acetyl-5,6-dihydro-2H-1,2-oxazines.

✍ Scribed by Pavel E. Ivashkin; Alexey Yu. Sukhorukov; Oleg L. Eliseev; Alexey V. Lesiv; Yulja A. Khomutova; Sema L. Ioffe


Publisher
John Wiley and Sons
Year
2008
Weight
44 KB
Volume
39
Category
Article
ISSN
0931-7597

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A Convenient Procedure for the Synthesis of 4,6-Disubstituted 2-Oxo-2H-pyran-5-carboxylic Esters. -The Michael addition products of Ξ²-ketoester anions of (I) with acetylenic esters (II) readily cyclize under basic reaction conditions to give 2H-pyran-2-ones (III) (8 examples). -(COVARRUBIAS-ZUNIGA,