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ChemInform Abstract: A Concise Approach to the Tricyclic Core of the Cytotoxic Marine Alkaloid Madangamine A.

โœ Scribed by N. MATZANKE; R. J. GREGG; S. M. WEINREB; M. PARVEZ

Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
28
Category
Article
ISSN
0931-7597

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Total Synthesis of the Potent Antitumor Agent Roseophilin: A Concise Approach to the Macrotricyclic Core. -The first synthesis of the intricate macrotricyclic core segment (XIV) of the title antibiotic is presented. The approach merges the potential of an established Pd-catalyzed macrocyclization r