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ChemInform Abstract: A Chemoenzymatic Synthesis of the Carbobicyclic Core Associated with CP-225,917 and CP-263,114 (Phomoidrides A and B).

✍ Scribed by Martin G. Banwell; Kenneth J. McRae; Anthony C. Willis

Publisher: John Wiley and Sons
Year: 2010
Weight: 31 KB
Volume: 33
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200209250

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The stunning molecular structures [1] coupled with the promising biological activities of the CP compounds (pho-moidrides, [2] 1 a and b; Figure 1) have inspired numerous studies directed at their total synthesis. [3] In 1999 we reported the first total synthesis of these molecules in their racemic

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