ChemInform Abstract: A Catalytic Enantioselective Approach to Chromans and Chromanols. A Total Synthesis of (-)-Calanolides A (IX) and B (VIII) and the Vitamin E Nucleus (XIII).

✍ Scribed by B. M. TROST; F. D. TOSTE

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 34 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199907271

✦ Synopsis

A Catalytic Enantioselective Approach to Chromans and Chromanols. A Total Synthesis of (-)-Calanolides A (IX) and B (VIII) and the Vitamin E Nucleus (XIII). -The key steps in the synthesis of the title compounds are regio-and enantioselective allylic alkylation of phenols and subsequent ring closure.