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ChemInform Abstract: A Carbonyl Oxide Route to Antimalarial Yingzhaosu A Analogues: Synthesis and Antimalarial Activity.

โœ Scribed by P. M. O'NEILL; N. L. SEARLE; K. J. RAYNES; J. L. MAGGS; S. A. WARD; R. C. STORR; B. K. PARK; G. H. POSNER


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
29
Category
Article
ISSN
0931-7597

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Synthesis and Activity of Some Antimalarial Bisquinolinemethanols. -Ongoing interest in the development of novel antimalarial agents leads to the synthesis of compounds such as (III) and (VIII). Among all compounds the derivative (VIIIb) shows high biological activity, but the toxicity of this subs