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ChemInform Abstract: 5a-Carba-β-D-, 5a-Carba-β-L- and 5-Thio-β-L-xylopyranosides as New Orally Active Venous Antithrombotic Agents.

✍ Scribed by P. RENAUT; J. MILLET; C. SEPULCHRE; J. THEVENIAUX; V. BARBEROUSSE; V. JEANNERET; P. VOGEL

Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis

5a-Carba-β-D-, 5a-Carba-β-L-and 5-Thio-β-L-xylopyranosides as New Orally Active Venous Antithrombotic Agents. -The title compounds, e.g. (VI) and (XIII), are prepared as antithrombotic agents. Compound (+)-(VI) is at least four times less active than its enantiomer, while (+)-(XIII) exhibits 50% of the antithrombotic activity of its antipode. -(RENAUT,

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