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5a-Carba-β-D-, 5a-Carba-β-L- and 5-Thio-β-L-xylopyranosides as New Orally Active Venous Antithrombotic Agents

✍ Scribed by Patrice Renaut; Jean Millet; Christiane Sepulchre; Jocelyne Theveniaux; Véronique Barberousse; Vincent Jeanneret; Pierre Vogel


Publisher
John Wiley and Sons
Year
1998
Tongue
German
Weight
159 KB
Volume
81
Category
Article
ISSN
0018-019X

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ChemInform Abstract: 5a-Carba-β-D-, 5a-C
✍ P. RENAUT; J. MILLET; C. SEPULCHRE; J. THEVENIAUX; V. BARBEROUSSE; V. JEANNERET; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

5a-Carba-β-D-, 5a-Carba-β-L-and 5-Thio-β-L-xylopyranosides as New Orally Active Venous Antithrombotic Agents. -The title compounds, e.g. (VI) and (XIII), are prepared as antithrombotic agents. Compound (+)-(VI) is at least four times less active than its enantiomer, while (+)-(XIII) exhibits 50% of