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ChemInform Abstract: 3′,5′-O-Phosphonoalkylidene Derivatives of 1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine: Synthesis and Reactivity.

✍ Scribed by M. ENDOVA; M. MASOJIDKOVA; M. BUDESINSKY; I. ROSENBERG

Publisher: John Wiley and Sons
Year: 2010
Weight: 44 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199850263

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Synthesis and Antiviral Activities of 5-Substituted 1-(2-Deoxy-2-C-methylene-4-thio-β-D-erythro-pentofuranosyl) uracils. -A variety of the title nucleosides [cf. (VII)/(VIII), (X)] are prepared using sila-Pummerer-type glycosylation as key step. The majority of the β-anomers of these nucleosides po