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ChemInform Abstract: 3-Chloropropyl Phenyl Ether as a 1,3-Dilithiopropane Source: Sequential Reaction with Carbonyl Compounds.

โœ Scribed by Francisco Foubelo; Miguel Yus


Book ID
101873983
Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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3-Chloropropyl phenyl ether as a 1,3-dil
โœ Francisco Foubelo; Miguel Yus ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 193 KB

The reaction of 3-chloropropyl phenyl ether (1) with lithium powder and a catalytic amount of DTBB (2.5% molar) in THF at -78ยฐC followed by successive treatment with a carbonyl compound [El = ButCHO, Me2CO, (CH2)5CO] at -78 to 20ยฐC and, after 1 h at this temperature, a second one [F~ = ButCHO, PhCHO